tors, the equine biological passport will become ain Allgemein 21.04.2018 06:35
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LONDON -- Garbine Muguruzas first major tournament as a reigning Grand Slam champion didnt last long.Less than a month after winning the French Open, the second-seeded Spaniard was beaten in the second round of Wimbledon on Thursday by a Slovakian qualifier ranked No. 124.In the biggest upset of the tournament so far, Jana Cepelova beat a listless Muguruza 6-3, 6-2 on Court 1 in less than an hour to reach the third round at the All England Club.Muguruza was not as sharp Thursday as she was in this tournament last year, when she lost to Serena Williams?in the final, or as she was in beating Williams in the final at Roland Garros this month for her first major championship.My energy was missing a little today, Muguruza said. From yesterday I felt a little bit tired. During the match and after the match, Im like, Tough day today, empty today.She sprayed ugly shots all over the court Thursday and finished with 22 unforced errors compared to just nine winners. Cepelova had a first-serve percentage of just more than 40 percent but still outplayed Muguruza with 14 winners and 12 errors.She played great, no fear, trying a lot of stuff that was working, Muguruza said. But my energy wasnt there. I was trying but it didnt work at all.Cepelova, Slovakias No. 5 female player, had to win three matches in qualifying to make it into the main draw. Its not the first time she has knocked off a top player. Cepelova ousted Simona Halep in the first round at Wimbledon last year, also on Court 1, and beat Williams at a tournament in Charleston in 2014.Last year I beat Halep on the same court and I had great memories, the 23-year-old Cepelova said. I am so happy.The last time a second-seeded woman lost at Wimbledon before the third round was in 2013, when?Victoria Azarenka?was beaten in the second round.Five-time Wimbledon champion Venus Williams won yet another match at the All England Club as three American women picked up victories as the tournament scrambled to get back on schedule.The eighth-seeded Williams, at 36 the oldest player seeded in the top eight at a major tournament since Martina Navratilova at Wimbledon in 1994, beat Greek qualifier Maria Sakkari 7-5, 4-6, 6-3 to reach the third round.It turned out to be an unexpectedly close, 2?-hour match between Williams, winner of seven Grand Slam titles and playing in her 19th Wimbledon, and Sakkari, making her first appearance at Wimbledon and third at a major.Williams, who had 38 winners but 31 unforced errors, won the most recent of her five Wimbledon titles in 2008. Since 2011, she has not been past the fourth round.Third-seeded Agnieszka Radwanska, the 2012 runner-up at Wimbledon, saved three match points and came back to beat 18-year-old Croatian Ana Konjuh, who accidentally stepped on a tennis ball and injured her right ankle in the next-to-last game.Radwanska pulled out the 2-6, 6-4, 9-7 victory in the second round after the 103rd-ranked Konjuh was broken while serving for the victory at 5-4 and 6-5 in the third set.Radwanska has made it to at least the semifinals at Wimbledon in three of the past four years.With play starting earlier on the outside courts after two days of bad weather, Madison Keys and Sloane Stephens?also advanced Thursday.Keys, seeded No. 9 after breaking into the top 10 for the first time this month, reached the third round with a 6-4, 4-6, 6-3 win over Kirsten Flipkens. Keys, a quarterfinalist last year, had 48 winners -- more than double the Belgian players 22.No. 18 Stephens, who reached the quarterfinals here in 2013, defeated Chinas Peng Shuai 7-6 (5), 6-2 in a first-round match that was delayed.Other womens winners included fourth-seeded Angelique Kerber advancing with a 6-1, 6-4 win over Varvara Lepchenko?and No. 5 Simona Halep, who beat Francesca Schiavone 6-1, 6-1. No. 14 Samantha Stosur was knocked out 6-4, 6-2 by 2013 runner-up Sabine Lisicki.No. 11?Timea Bacsinszky?beat Luksika Kumkhum 6-4, 6-2,?Annika Beck?ousted Britains Heather Watson 3-6, 6-0, 12-10, and Frances Kristina Mladenovic, seeded No. 31, was eliminated 6-3, 6-3 by Aliaksandra Sasnovich. Donne NMD R1 Adidas Rosa/Bianche . Louis. To which I would say two things: 1. Where there is smoke, there is or perhaps has been a little fire. Or, in other words, the two teams would appear to have at least spoken. And spoken is defined as one calling the other to inquire, no more, no less. Stan Smith Bianche Saldi . During the athletes parade, the 23-strong Ukrainian team was represented by a lone flagbearer in an apparent protest at the presence of Russian troops in Ukraines Crimean peninsula. http://www.nmdcs2nere.it/sconti-scarpe-adidas-stan-smith-bianche-30.html .C. -- After a listless first half, the Washington Wizards used a big third quarter run to beat the Charlotte Bobcats Bradley Beal scored 21 points and the Wizards used a 17-0 run in the third quarter to take control of what had been a close game and beat the Bobcats 97-83 on Tuesday night. Uomo NMD Human Race Pharrell x adidas Bianche/Colorful . Perhaps Carroll was so prepared for a break because he believes there is very little the Seattle Seahawks need heading into the off-season. "I dont see anything that we need to add. We just have to get better," Carroll said. Adidas Gazelle Uomo Scontate .7 million, one-year contract, a raise of $2.2 million. Wieters had asked for $8.75 million and the Orioles had offered $6. Lets concede for a moment that some people will cheat to win. I know, its hard to swallow. But human nature, being driven by human beings, sometimes veers toward the dark side, and it is up to those who prefer to play the game on the square to make cheating a no-win option.To that end, it was announced last week by the California Horse Racing Board that the Ken Maddy Laboratory at UC-Davis will be going full speed ahead in developing the same kind of athletic biological passport (ABP) being applied to participants in such international sports as cycling, track and field, and World Cup soccer.In order to monitor the new generation of doping agents, were going to have to develop biological passports, said Rick Arthur, CHRB equine medical director. Remember, its always a cat-and-mouse game. Whenever we plug up one problem, they start looking for a new and better treatment.A biological passport would record the normal blood profile of every horse in competition. Pre-race and out-of-competition testing would require that the horse maintains his normal profile.Arthur cites the illegal use of anabolic steroids and blood-doping agents as the two primary targets of the biological-passport project. The first study module for the Maddy lab would be an ABP that would indicate abnormalities in the natural biosynthesis of equine testosterone.We know the effects anabolic steroids have on the muscles last well beyond the presence of the drug and because of that are not detectable with our normal testing, Arthur said. We think we can measure abnormalities in the steps along the way that indicate the animal has been doped with an anabolic agent.The idea of an equine biological passport is gaining supporters. Jonathan Allen, a practicing vet based in south Florida, became a believer after a reputable lab tested the blood of two groups of horses in his care. One of the sample groups had recently arrived from another racing region.We know things like cobalt and EPO are used to enhance oxygen delivery to muscles, Allen said. But the traditional tests for blood doping are expensive and unreliable.Allen is an amateur club cyclist who does not need to look far to see the likely effects of blood enhancement.There are probably guys I cycle with that are going all the time to these wellness clinics and are doing HGH, testosterone, Allen said. Im from Boca Raton, the land of ever young. My neighbor is 72, pumping iron, wearing testosterone patches - all under a doctors prescription.The biological passports of human athletes contain a blood measure that accounts for the normal distribution and width (RDW) of red blood cells. A simple, pre-race blood test for racehorses would need to conform closely to the informationn established in their personal passport.dddddddddddd A marginally abnormal reading would require a follow-up test, while dramatic abnormalities would be cause for the horse to be scratched.Dr. Raquel Walton, the equine pathologist, has written that there are three main reasons for RDWs to be abnormal in horses, Allen said. The first would be some kind of hemolytic anemia, where your horse is sick and not producing a sufficient amount of red blood cells. The second would be a massive blood loss. And the third one would be if the horse was given EPO or another substance that stimulates red blood cells above and beyond the normal level.It stands to reason that an anemic horse or a horse who has just suffered a large blood loss would not be doing much training, let alone be entered to race.This is not looking for the smoking gun, Allen said. Its looking for the crime scene. There is no positive called, no suspensions or fines, and no cause for a trainer to lawyer up. It is a biological pre-race examination, just as horses are required to pass a pre-race physical examination and could be scratched for a suspicious tendon.No one supporting the biological-passport concept is suggesting that it will replace conventional small-molecule drug testing since analgesics and stimulants do not alter RDW benchmarks. The best comparison, according to Arthur, is the pre-race testing instituted in California and other jurisdictions several years ago for total carbon dioxide levels in the blood. Levels above a certain threshold were indicative of a practice known as milkshaking.We now have about 300,000 TCO2 levels in our database, Arthur said. We can follow a horses levels from start to start, from barn to barn. You just have to let people know youre paying attention.And when, Arthur was asked, was the last high TCO2 called in California?We havent had one in two years, he replied.With more persuasive pressure from veterinarians like Arthur and Allen, in both public and private sectors, the equine biological passport will become a reality, and horse racing will join the 21st century when it comes to policing its players. Hopefully, California will be the first of many racing jurisdictions to make such a commitment.It may be ambitious, but weve set a goal to be able to have a fairly good data test for this a year from now, Arthur said, referring to the biological passport for anabolic steroids. This is important, and Im excited about the prospects. I think most people realize that if we cant provide real integrity for horse racing -- not just the perception -- then nothing works. 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